Aromaticity lost: In the presence of [{Ir(cod)Cl}2] and a binol-derived phosphoramidite ligand, spirocyclohexadienone derivatives were obtained with up to 97 % ee through iridium-catalyzed intramolecular asymmetric allylic dearomatization of phenols (see scheme; cod=cycloocta-1,5-diene).
No takes yet. Share an insight, caveat, or question.
Wu et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: