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Physiological study demonstrates sex-specific beta-adrenergic regulation of arterial dilation during exercise in young adults, suggesting females rely more on these receptors for vascular tone.
We examined the role of beta-adrenergic receptors (β-ARs) in mediating exercise hyperemia in males and females. No sex differences in leg blood flow or leg vascular conductance, but females exhibited greater dilation of the femoral artery (FA), and β-AR blockade blunted FA dilation in females at absolute exercise intensities. Findings highlight that exercise hyperemia is not reliant on β-ARs and suggest females rely more on β-ARs in mediating vascular tone during exercise.
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Thompson et al. (2025) studied this question.
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