Thrombotic Thrombocytopenic Purpura: A Review of the Literature With Report of a Case

Article1 March 1958THROMBOTIC THROMBOCYTOPENIC PURPURA: A REVIEW OF THE LITERATURE WITH REPORT OF A CASEEARL H. ANTESEARL H. ANTESSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-3-512 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThrombotic thrombocytopenic purpura has become recognized as a clinical entity only in recent years. This uniformly fatal disease, which may affect either sex at any age, is characterized by the clinical triad of hemolytic anemia, thrombocytopenic purpura and varied central nervous system abnormalities. The pathologic picture primarily shows changes in the arterioles, with the formation of poorly understood hyaline thrombi.It is the purpose of this paper to review the available literature on this subject and to add a case report. 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MACGILLVIRAY, M.D., REUBEN MERLISS, M.D., F.A.C.P., HARRY SACKS, M.D. 1 March 1958Volume 48, Issue 3Page: 512-536KeywordsArteriolesCentral nervous systemHemolytic anemiaHypertensionNauseaPancreasSmallpoxThrombotic thrombocytopenic purpura ePublished: 1 December 2008 Issue Published: 1 March 1958 PDF downloadLoading ...