Why the study?
Stent use in the acute phase of ruptured anterior cerebral artery dissection carries a high risk of ischemic complications.
Prasugrel administration and dynamic modification of antiplatelet therapy may allow safe stent use in the acute phase of ruptured anterior cerebral artery dissection.
Dynamic antiplatelet regimens with prasugrel may enable acute stenting in ruptured ACA dissection; single-case data leave broader safety unproven.
A case of ruptured anterior cerebral artery (ACA) dissection was treated with multiple neck-bridge stents, with modification of antiplatelet administration according to changes in the shape of the aneurysm in the acute phase. A 67-year-old woman presented with severe subarachnoid hemorrhage and fusiform dilatation was observed in the left ACA between the A1 and A2 segments. The use of stents in the acute phase is associated with high risk of ischemic complications. Prasugrel administration, which is considered to have low drug resistance, may have allowed safe stent use in the acute phase.
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Otaki et al. (2021) studied this question.
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