Why the study?
Does advanced age (≥80 years) affect mortality, length of stay, and the ability to tolerate complications following emergency laparotomy?
Does advanced age (≥80 years) affect mortality, length of stay, and the ability to tolerate complications following emergency laparotomy?
Elderly patients undergoing emergency laparotomy experience higher mortality not because of a higher frequency of complications, but due to a reduced physiological reserve to tolerate them.
Octogenarians show higher mortality after emergency laparotomy from reduced complication tolerance; this leaves open whether age-specific resilience strategies improve outcomes.
Thirty-day mortality following emergency laparotomy is high, and greater amongst elderly patients. Studies systematically describing peri-operative complications are sparse, and heterogeneous. We used the postoperative morbidity survey to describe the type and frequency of complications, and their relationship with outcomes for 144 patients: 114 < 80 years old, and 30 ≥ 80 years old. Cumulative postoperative morbidity survey scores and patterns of morbidity were similar (p = 0.454); however, 28-day mortality was higher in the elderly (10/30 (33.3%) vs. 11/114 (9.6%), p = 0.008), and hospital stay was longer (median (IQR [range]) 17 (13-35 [6-62]) days vs. 11 (7-21 [2-159]) days, p = 0.006). Regression analysis indicated that cardiovascular, haematological, renal and wound complications were associated with longer hospital stay, and that cardiovascular complications predicted mortality. The postoperative morbidity survey system enabled structured mapping of the number and type of complications, and their relationship with outcome, following emergency laparotomy. These results indicate that rather than a greater propensity to complications following surgery, it was the failure to tolerate these that increased mortality in the elderly.
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Howes et al. (2015) studied this question.
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