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It has always been assumed that the numerous members of the huge GPCR family of receptors function in isolation. However, as [Graeme Milligan][1] discusses in a Perspective, a host of new findings ([ Rocheville et al .][2]) now suggest that related but different GPCRs can bind to each other, and when they do their properties are altered. [1]: http://www.sciencemag.org/cgi/content/full/288/5463/65 [2]: http://www.sciencemag.org/cgi/content/full/288/5463/154
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Graeme Milligan (2000) studied this question.
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