Why the study?
Does peripartum Holter monitoring and cTnI analysis identify myocardial ischaemia in normal patients undergoing elective Caesarean section?
Does peripartum Holter monitoring and cTnI analysis identify myocardial ischaemia in normal patients undergoing elective Caesarean section?
This study provides the first evidence of actual myocardial ischaemia (elevated cTnI) occurring in conjunction with ECG changes during elective Caesarean section.
Answers are grounded in this paper and cite their sources.
Findings from this small cohort are hypothesis-generating; do not support routine troponin or Holter monitoring in low-risk elective Caesarean sections.
Incidence rates of electrocardiographic changes during Caesarean section vary from 25 to 60%. To date, no investigator has identified myocardial ischaemia resulting from these changes. We investigated patients undergoing elective Caesarean section using peripartum Holter monitoring and serum analysis of cardiac troponin I (cTnI). Twenty-six patients presenting for elective Caesarean section were studied. Peroperative Holter monitoring continued for 12 h postoperatively, at which time blood samples for cTnI levels were taken. Significant ST changes were recorded in 42% of patients peroperatively and 38.5% of patients postoperatively. Forty-two per cent of patients experienced peroperative chest pain requiring opioid analgesia. Chest pain was significantly associated with abnormal electrocardiogram (ECG) findings. Ischaemic levels of cTnI were recorded in two patients. This study reports, for the first time, myocardial ischaemia (7.69% of patients) arising in conjunction with the ECG changes seen during elective Caesarean section. We also report episodes of significant postoperative ST-segment changes.
No takes yet. Share an insight, caveat, or question.
Moran et al. (2001) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: