Drug-induced subacute cutaneous lupus erythematosus initially diagnosed as erythema annulare centrifugum

Introduction: An undesirable consequence of modern medicine and pharmacology is the occurrence of drug reactions.Drug-induced cutaneous reactions account for approximately 70% of all clinical manifestations of adverse drug effects.This can be attributed to the fact that the skin, a signaling organ, is the largest body organ and exhibits significant metabolic/immunological activity.Case report: We present the case of a woman with drug-induced subacute cutaneous lupus erythematosus, primary diagnosed as erythema annulare centrifugum, who was hospitalized in the in the Department of Dermatology.Conclusions: Knowing that the prevalence of drug-induced subacute cutaneous lupus erythematosus appears to be considerably higher (70%) than previously estimated (20%), the diagnosis of drug-induced subacute cutaneous lupus erythematosus should also be considered when idiopathic subacute cutaneous lupus erythematosus is suspected, particularly if several therapeutics are utilized in patients older then 60 years.