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Not all transcribed RNAs are protein-coding. Some non-coding RNAs (ncRNAs) seem to be non-functional and are resulted from spurious transcription. Many others have a significant function in the translation process. Gene expressions depend on complex networks of diverse gene regulatory pathways. Several ncRNAs, as major elements, regulate gene expression in a sequence-specific system either at the transcriptional level or post-transcriptional level. RNA-mediated gene regulation machinery is evolutionarily ancient and pretty complex. In this review, the current knowledge in the field of RNA-mediated gene silencing have been summarized.
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Hajieghrari et al. (2021) studied this question.
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