Isolation and Total Synthesis of Icumazoles and Noricumazoles—Antifungal Antibiotics and Cation‐Channel Blockers from Sorangium cellulosum

Joint efforts: The antifungal icumazole A, the potassium-ion-channel inhibitor noricumazole A, and their glycosylated derivatives are new, structurally related secondary metabolites isolated from Sorangium cellulosum. Their structures have been fully assigned by a joint strategy that relied on spectroscopy, derivatization, fragmentation, and finally the first total synthesis of noricumazole A.