Answers are grounded in this paper and cite their sources.
Three cases of poorly differentiated endometrial adenocarcinoma showing trophoblast-like differentiation are reported. The multinucleated, syncytiotrophoblast-like cells were strongly positive for beta-human chorionic gonadotropin (beta-HCG) by immunohistochemical study. High levels of beta-HCG were also present in the patients' serum, but dropped significantly after treatment. The patients had an unusually rapid and progressive clinical course with widespread dissemination and death by tumor.
No takes yet. Share an insight, caveat, or question.
Pesce et al. (1991) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: