Why the study?
Hypertrophic cardiomyopathy phenotypic changes extend beyond ventricular hypertrophy, and differential diagnosis among multiple causes of hypertrophy is difficult.
Cardiac magnetic resonance imaging is a fundamental tool for the diagnostic and prognostic evaluation of hypertrophic cardiomyopathy.
Hypertrophic cardiomyopathy, the most common genetic cardiopathy in the general population, is characterized by asymmetric left ventricular hypertrophy. However, the phenotypic changes in this cardiomyopathy extend beyond ventricular hypertrophy and include changes in the mitral valve apparatus, papillary muscles, and right ventricle. Due to the difficult differential diagnosis among multiple causes of hypertrophy, cardiac magnetic resonance has played a fundamental role in its diagnostic and prognostic evaluation; magnetic cine-resonance in defining the location and extent of hypertrophy; late enhancement, in the detection of areas of myocardial fibrosis; more recent techniques such as T1 mapping that assesses interstitial fibrosis and extracellular volume; and finally tissue tracking in the analysis of myocardial deformation.
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Valério et al. (2022) studied this question.
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