Answers are grounded in this paper and cite their sources.
The rates of transcription of particular regions of DNA appear to be limited primarily by the frequencies with which RNA polymerase can utilize a diversity of specific DNA sequences (promoters) to initiate transcription. The 1000-fold range of RNA initiation frequencies observed in vivo is thought to reflect this diversity of promoter sequences; consequently, the investigation of transcriptional selectivity in Escherichia coli has focused largely on the relationship of promoter structure to initiation frequency. How, then, does promoter structure determine initiation frequency?
No takes yet. Share an insight, caveat, or question.
McClure et al. (1983) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: