A 12–week, observer‐blind, study compared doxycycline (50 mg daily) with minocycline (50 mg twice daily) in the treatment of acne vulgaris in 4.1 patients. The analysis of data on 34 patients completing the study (15 receiving doxycycline and 19 receiving minocycline) showed both treatments to be equally effective, although the use of doxycycline had the advantage of it being a once‐daily treatment regime. Doxycycline, with minimal side effects, can be recommended for the treatment of acne vulgaris.
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P.V. Harrison (1988) studied this question.
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