The efficacy and tolerability of a new formulation of slow-release indomethacin tablet was compared in a double-blind cross-over manner with a conventional indomethacin capsule in 30 patients with ankylosing spondylitis. Gastrointestinal side-effects and dizziness were less frequent during the slow-release tablet period than during the capsule period.
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Lehtinen et al. (1984) studied this question.
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