Pulmonary Aspergilloma

EXCEPT for pulmonary resection in selected cases, the therapy of pulmonary aspergillosis has been generally ineffective. Nevertheless, in isolated cases, cures have followed the administration of nystatin by mouth1 and by aerosol2 and the parenteral injection of stilbamidine.3 More recently, the administration of 24 to 30 gm. of potassium iodide by mouth in 2 cases4 and of amphotericin B intravenously in another5 was also thought to be therapeutically effective. However, the drug intolerance and electrolyte imbalance resulting from large doses of iodides taken by mouth4 and the systemic and renal toxic effects of intravenously administered amphotericin6 , 7 prevent a casual approach . . .