Why the study?
What is the prevalence, clinical course, and what are the risk factors for pericardial effusions in adolescent girls with anorexia nervosa?
What is the prevalence, clinical course, and what are the risk factors for pericardial effusions in adolescent girls with anorexia nervosa?
Pericardial effusions are common and mostly asymptomatic in adolescent girls with severe anorexia nervosa, and they typically regress spontaneously with refeeding.
Pericardial effusions may warrant awareness during refeeding in severe adolescent anorexia nervosa; extends descriptive cardiac data but leaves optimal screening open.
The aim of this study was to evaluate cardiac, biochemical and endocrine differences between female adolescents with anorexia nervosa (AN) with and without pericardial effusions. We studied 128 female adolescents (9.8-17.7 years) with anorexia nervosa (AN) diagnosed according to DSM-IV (American Psychiatric Association, 1994) criteria. They all underwent an echocardiographic evaluation. In 29 patients (22.2 %) a pericardial effusion (ranging between >or= 0.35-2.5 cm) was noted. None of the patients were clinically symptomatic. After 3 months of refeeding, the effusions disappeared in 18/29 patients while in 7/29 patients a pericardial effusion > 0.3 cm persisted. Risk factors for development of effusions were a BMI <or= 13,5 kg/m(2), weight loss >or= 25% and IGF-1-level <or=100 ng/ml. Pericardial effusions are common in adolescent AN patients. They are mostly asymptomatic not requiring any intervention and spontaneously regress with refeeding. They are more common in the patients with the most significant weight loss.
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Docx et al. (2010) studied this question.
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