Repeated Spontaneous Pregnancies in 45,X Turner Syndrome

In Brief BACKGROUND: Spontaneous pregnancy rarely occurs in women with Turner syndrome, and poor maternal outcomes are prominent in these women. CASES: We report two women with 45,X Turner syndrome who had a total of four spontaneous pregnancies. Maternal and fetal outcomes were good despite maternal comorbidities. Cesarean deliveries were performed in two of the pregnancies because of aortic dilatation and fetopelvic disproportion. Both cases were initially diagnosed as primary amenorrhea (absent pubarche and menarche with serological hypogonadism). CONCLUSION: Repeated spontaneous pregnancies occur in women with 45,X Turner syndrome. Poor maternal outcome is not the rule. Repeated spontaneous pregnancies with good maternal and fetal outcomes may occur in women with amenorrheal hypogonadal 45,X Turner syndrome.