Journal Article Factorial trials in cardiology: pros and cons Get access J. LUBSEN, J. LUBSEN *Société poul la Recherche Cardiologique (SOCAR)Givrins, SwitzerlandErasmus University RotterdamThe Netherlands Correspondence: Prof. J. Lubsen, SOCAR SA. Domaine de Leydefeur, CH-1261 Givrins, Switzerland. Search for other works by this author on: Oxford Academic PubMed Google Scholar S. J. POCOCK S. J. POCOCK †Medical Statistics Unit, London School of Hygiene and Tropical MedicineLondon, U.K. Search for other works by this author on: Oxford Academic PubMed Google Scholar European Heart Journal, Volume 15, Issue 5, May 1994, Pages 585–588, https://doi.org/10.1093/oxfordjournals.eurheartj.a060552 Published: 01 May 1994
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Lubsen et al. (1994) studied this question.