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What is the rationale and current role of combined reperfusion strategies (facilitated PCI, pharmacoinvasive therapy, and rescue PCI) in STEMI?
What is the rationale and current role of combined reperfusion strategies (facilitated PCI, pharmacoinvasive therapy, and rescue PCI) in STEMI?
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This review outlines the rationale and evidence for combined reperfusion strategies in STEMI patients who cannot receive primary PCI within the recommended 90-minute window.
Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation myocardial infarction (MI), but most patients do not arrive at a PCI facility within the recommended 90 minutes of first medical contact. If delay is expected, timely thrombolysis is recommended, followed by early transfer for PCI. The authors review the rationale behind three combined reperfusion strategies-facilitated PCI, pharmacoinvasive therapy, and rescue PCI-and data on their effectiveness.
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Hanna et al. (2010) studied this question.
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