Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 1, 1994Journal of Biological ChemistryOpen Access

Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation.

View Full Paper
Ask AI
Bookmark
Share

Authors

JRJ M RuediScripps Research InstituteBBBernard BabiorBoston University

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Ruedi et al. (1994) studied this question.

synapsesocial.com/papers/6a7ed4f1f9627588bb79862ahttps://doi.org/10.1016/s0021-9258(17)37436-7
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The respiratory burst oxidase of human neutrophils. Guanine nucleotides and arachidonate regulate the assembly of a multicomponent complex in a semirecombinant cell-free system.1993 · 68 citations
  2. 2Purification of cytochrome b-245 from human neutrophils1984 · 91 citations
  3. 3Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils.1991 · 149 citations
  4. 4Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase.1992 · 176 citations
  5. 5Relationship of protein phosphorylation to the activation of the respiratory burst in human neutrophils. Defects in the phosphorylation of a group of closely related 48-kDa proteins in two forms of chronic granulomatous disease.1988 · 180 citations