Key result
Monitoring the venous pressure curve during cryoballoon ablation correlated with the extent of contrast agent leakage (Cohen's kappa 0.81; 95% CI 0.63-0.99).
Why the study?
To evaluate analyzing changes in the pulmonary venous pressure curve as an alternative to pulmonary venography for monitoring balloon-to-pulmonary vein adhesion during cryoballoon ablation.
Does monitoring pulmonary venous pressure curves correlate with contrast agent leakage during cryoballoon ablation in patients with symptomatic drug-refractory paroxysmal atrial fibrillation?
Observational
Does monitoring pulmonary venous pressure curves correlate with contrast agent leakage during cryoballoon ablation in patients with symptomatic drug-refractory paroxysmal atrial fibrillation?
Monitoring pulmonary venous pressure curves is a feasible and easy-to-perform alternative to venography for assessing balloon occlusion during cryoballoon ablation.
May reduce contrast use during cryoballoon PVI; leaves open outcome data needed for routine adoption.
Background: Cryoballoon ablation is safe and effective for pulmonary vein isolation in patients with symptomatic drug-refractory paroxysmal atrial fibrillation. To monitor adhesion between the balloon and the pulmonary vein, an alternative technique to pulmonary venography is to analyze changes in the pressure curve. Methods: We have described the adhesion level characterized by four types of pressure waveforms. Results: These correlated with the extent of contrast agent leakage (Cohen's kappa of 0.81 [IC 95%: 0.63-0.99]). Conclusion: Monitoring the venous pressure curve is easy to perform and has the advantage of being able to detect balloon movement during the first few seconds of treatment.
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Milhem et al. (2023) conducted an observational in Symptomatic drug-refractory paroxysmal atrial fibrillation. Venous pressure curve monitoring vs. Pulmonary venography was evaluated on Correlation with the extent of contrast agent leakage (Cohen's kappa 0.81, 95% CI 0.63-0.99). Monitoring the venous pressure curve during cryoballoon ablation correlated with the extent of contrast agent leakage (Cohen's kappa 0.81; 95% CI 0.63-0.99).
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