Clinical, electrocardiographic, and haemodynamic effects of long-term use of propranolol in Prinzmetal's variant angina pectoris.

A long-term administration of propranolol in 5 patients with Prinzmetal's angina pectoris was highly successful. The effect of the drug was evaluated on a clinical, electrocardiographic, and haemodynamic basis. In 4 patients the complete disappearance of the subjective symptoms, of the electrocardiographic alterations occurring during the anginal attacks, and of the associated haemodynamic changes was achieved. In one patient the anginal episodes became obviously less frequent and severe.