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December 15, 2004Cancer Research

Inhibition of Chk1 by CEP-3891 Accelerates Mitotic Nuclear Fragmentation in Response to Ionizing Radiation

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RSRandi G. SyljuåsenOslo University HospitalCSClaus Storgaard SørensenUniversity of CopenhagenJNJesper NylandstedUniversity of Southern Denmark

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Syljuåsen et al. (2004) studied this question.

synapsesocial.com/papers/6a7ee98edd8171d0d19a1ed2https://doi.org/10.1158/0008-5472.can-04-2434
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p531996 · 451 citations
  2. 2Chk1 Mediates S and G2 Arrests through Cdc25A Degradation in Response to DNA-damaging Agents2003 · 389 citations