How do we decide to de-isolate COVID-19 patients?

Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, the number of individuals affected by the disease has rapidly risen. 1,2It has been suggested that the disease is contagious during the incubation period in infected patients. 3However, the duration for which the disease remains contagious in the patients is not known.It is not known as to how and when can a decision be made to de-isolate these patients to avoid the transmission of the causative virus i.e. severe acute respiratory syndrome corona virus 2 (SARS-CoV-2).Serial collections of oropharyngeal swab and sputum specimens are recommended by the Taiwan Centers for Disease Control and Prevention (Taiwan CDC) to detect SARS-CoV-2 from the upper airways