High-Suitcordance Intelligent Fibers for Panvascular Disease Monitoring-Intervention

Panvascular diseases, sharing atherosclerosis as a common pathological basis, pose a significant threat to human health. Flexible fibers combined with sensing elements become implantable and interventional smart fibers with monitoring and intervention capabilities. Due to the prolonged course of panvascular diseases, higher requirements are imposed on the monitoring-intervention closed-loop system of flexible fibers—high suitcordance (a combination of short-term suitability and long-term concordance). Suitcordance implies that novel flexible fibers must meet the traditional concept of compatibility and satisfy the new requirement of long-term co-regulation of fiber-vascular fate. This review introduces emerging flexible fiber electronic devices with exceptional performance related to panvascular diseases. These devices adapt well to the complex panvascular environment and provide ideal technical support for real-time, non-invasive, and continuous health monitoring-treatment. However, existing devices have limitations, and future research should focus on developing novel flexible smart fibers based on the clinical needs of panvascular diseases. Graphical Abstract Flexible fiber technology can revolutionize the panvascular medical paradigm. Flexible fiber technology aids in promptly identifying panvascular disease indicators, enabling better personalized treatment. Further developments include wireless design, miniaturization, multifunction, artificial intelligence-assisted diagnosis, virtual medicine, customized healthcare, etc., and the integration of monitoring-intervention closed-loop functions.