In this case we evaluated brain tissue pO2, pCO2 and pH during ischemia and arterial oxygen desaturation (hypoxia). In both situations brain pO2 decreased. During ischemia, tissue pCO2 increased while pH decreased; but both pCO2 and pH were stable during hypoxia. These results suggest that brain tissue pO2, pCO2 and pH measures provide information on tissue perfusion and oxygen availability during ischemia and hypoxia.
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Hoffman et al. (1996) studied this question.
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