Survival Evaluation in Patients Over 70 Years of Age With Advanced Stage Non-small Cell Lung Cancer

Patients Over 70 Years of Age With Advanced Stage Non-small Cell Lung Cancer[3] Non-small cell lung cancer (NSCLC) that accounts for 85% of all lung cancers is usually diagnosed at advanced stages. [4]It is known that 30 to 40% of lung cancer patients are older than 70 years. [1,4]So, the majority of the new cases of lung cancer are elderly NSCLC patients. [5]ntroversy remains about the cut-off point of age for the definition of elderly.Although medical oncologists have considered the age of 65 years for this purpose, it is speculated that a cut-off value of 65 years is not representative of the older population. [6]In the light of those explanations, 70 years have been accepted for the limit of senescence and the geriatric period in some studies.Objectives: Non-small cell lung (NSCLC) cancer is usually seen in elderly patients.The impact of over 70 age on the survival of patients with NSCLC has not been studied.This study aimed to evaluate the impact of demographic and clinical variables on survival in Stage IV the NSCLC elderly patient.Methods: This study was a retrospective cohort analysis of 244 patients with advanced stage NSCLC, between January 2015 and December 2019.The patients were classified as the <70 years and ≥70 years.The primary and secondary outcomes were the overall survival and the impact of the demographics and clinical variables on survival, respectively.Results: The numbers of patients who were <70 and ≥70 years were 136 (55.7%) and 108 (44.3%), respectively.Although the overall survival in patients aged 70 years or older was shorter than that of the younger patients, the difference was statistically insignificant (p=0.236).Weight loss, ≥2 comorbidities and TNM stage IV were significantly associated with shorter overall survival.