Key result
Postural change with ear-oximetry dye dilution assesses cardiac output changes in ischemic heart disease.
Why the study?
Direct hemodynamic assessment of cardiac function is desirable, as extensive investigations are not usually admissible in patients with ischaemic heart disease. This study sought to describe a myocardial function test measuring cardiac output changes during postural change from upright to recumbent and compare responses in normal subjects and patients with ischaemic heart disease.
Does a standard postural change from upright to recumbent alter cardiac output and stroke volume differently in patients with ischaemic heart disease compared to normal subjects?
Observational
Does a standard postural change from upright to recumbent alter cardiac output and stroke volume differently in patients with ischaemic heart disease compared to normal subjects?
Describes a non-invasive hemodynamic test of myocardial function in patients with ischaemic heart disease using postural changes and dye dilution.
A direct hemodynamic assessment of cardiac function in man is a desirable addition to a clinical appraisal of the cardiovascular system.Cardiac performance, however, involves many factors and while it is possible to analyse some of these in animal experiments, extensive investigations are not usually admissible in patients with ischmmic heart disease.McMichael and Sharpey-Schafer (1944) showed in normal subjects that by changing the posture from the upright to recumbent position the cardiac output and stroke volume were raised.These observations have been used as a basis for a test of myocardial function in which changes of cardiac output are measured by dye dilution and the photoelectric earpiece technique.The purpose of this paper is to describe such a test, to give the results when applied to normal subjects and to patients with ischaemic heart disease, and to discuss their significance in relation to the clinical findings.
No takes yet. Share an insight, caveat, or question.
Thomas et al. (1965) conducted an observational in Ischaemic heart disease. Standard postural change test (upright to recumbent position) with dye dilution and photoelectric earpiece technique vs. Normal subjects was evaluated on Changes in cardiac output and stroke volume. Standard postural change testing using dye dilution and a photoelectric earpiece was evaluated to measure cardiac output in ischaemic heart disease (quantitative results not stated in abstract).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: