Key result
Targeted case-finding for chronic kidney disease in high-risk populations using serum creatinine and urine albumin can protect kidney health and reduce global disease burden.
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Early identification of kidney disease through targeted case-finding or population screening can decrease the global burden of CKD and cardiovascular disease.
Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease risk, and decrease mortality. We must ask "Are your kidneys ok?" using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing for diabetes and measurement of blood pressure and body mass index. This World Kidney Day we assert that case-finding in high-risk populations, or even population level screening, can decrease the burden of kidney disease globally. Early-stage CKD is asymptomatic and simple to test for, and recent paradigm shifting CKD treatments such as sodium glucose co-transporter-2 inhibitors dramatically improve outcomes and favor the cost-benefit analysis for screening or case-finding programs. Despite this, numerous barriers exist, including resource allocation, health care funding, health care infrastructure, and health care professional and population awareness of kidney disease. Coordinated efforts by major kidney nongovernmental organizations to prioritize the kidney health agenda for governments and aligning early detection efforts with other current programs will maximize efficiencies.
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Vassalotti et al. (2025) conducted an editorial in Chronic Kidney Disease. Early detection of chronic kidney disease was evaluated. Targeted case-finding for chronic kidney disease in high-risk populations using serum creatinine and urine albumin can protect kidney health and reduce global disease burden.
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