Bone Mineral Density Response to Estrogen Replacement in Frail Elderly Women

-teoporoticfracturesisinwomenolder than 75 years, who con-stitutearapidlyexpandingseg-ment of the US population. Bone min-eral density (BMD), which is a strongriskfactorforosteoporosis,continuestodecline with age. Indeed, recent pro-spective studies indicate that bone lossnotonlycontinuesfrommiddleageintoold age but may in fact accelerate in el-derlypersons.