Polyion complex nanoparticles based on 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt (PSA) and stimuli-responsive PEGylated nanogels composed of PEG tethered chains and a cross-linked poly[2-(N,N-diethylamino)ethyl methacrylate] gel core containing gold nanoparticles showed a remarkable regulation of the fluorescence signal synchronizing with the multi-stimuli-triggered release of the PSA in response to pH, temperature and light.
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Oishi et al. (2009) studied this question.
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