Dedifferentiated solitary fibrous tumour of the nasal cavity: the first case reported with molecular characterization of a TP53 mutation

to stroma, suggesting a role for invadopodia in local invasiveness.At ameloblastoma invasion sites cortactin would recruit MT-MMP, inducing focal degradation in stroma.Correlating cortactin and MT1-MMP presence in ameloblastoma with our previous findings on MMPs and growth factors, 3,4 we suggest that cortactin, MT1-MMP, proteases and growth factors would combine forces to regulate ameloblastoma invasiveness.We demonstrated cortactin and MT1-MMP expression in ameloblastoma.These proteins were increased significantly compared to CCOT, a non-invasive odontogenic tumour.Our results indicate that invadopodia proteins cooperate to regulate ameloblastoma invasion.