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Demonstrates that lower serum albumin levels correspond to poorer functional recovery in acute ischemic stroke patients, indicating its potential value as a prognostic biomarker.
Background Stroke is becoming an important cause of premature death and disability in low- income and middle-income countries like India, largely driven by demographic changes and enhanced by the increasing prevalence of the key modiable risk factors. Despite early initiation of treatment protocols, there may be long lasting debilitating sequel. Therefore, there has been a search for neuroprotective agents which might improve the prognosis of stroke. Methods Study was conducted at MGM Medical College and Hospital, Navi-Mumbai where in 75 patients admitted with acute ischemic stroke selected for the study. Proper consent was taken from the patients after checking the inclusion criteria. Their serum albumin levels were checked at the time of admission and discharge and Modied Rankin score was calculated to assess functional status. Results The mean serum albumin levels at the time of admission was 3.86 ± 0.49 g/dL and the mean serum albumin levels at discharge were 3.95 ± 0.47 g/dL. Approximately 73.32% of the cases had MRS score up to 3 had serum albumin levels of 4.0 to 4.49 g/dL and 27% had MRS score more than 3 had albumin level 3 – 3.99 g/dL. Conclusion It is concluded that low serum albumin levels are associated with poor functional outcomes as reected by an increase in MRS score. Thus, in general, low serum albumin levels are associated with worse functional outcomes.
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Ahmed et al. (2023) studied this question.
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