Answers are grounded in this paper and cite their sources.
Familial hemophagocytic lymphohistocytosis (HLH) includes several genetic disorders of immune-cell regulation that commonly lead to death if not diagnosed and treated promptly. In this issue of Blood, Bryceson and colleagues provide new insights into the pathogenesis of a subtype of HLH caused by germline mutations in STX11, the gene encoding syntaxin-11.
No takes yet. Share an insight, caveat, or question.
Kim E. Nichols (2007) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: