Why the study?
Current therapeutic approaches for diabetic kidney disease have significant limitations, whereas Traditional Chinese Medicine shows potential to modulate multiple pathological pathways.
This review highlights the multifaceted therapeutic mechanisms of Traditional Chinese Medicine in managing diabetic kidney disease.
Diabetic kidney disease (DKD) is a severe complication of diabetes and a leading cause of end-stage renal disease (ESRD). It is characterized by a complex pathogenesis that involves genetic, epigenetic, metabolic, and multifactorial elements. Current therapeutic approaches for DKD have significant limitations. In contrast, Traditional Chinese Medicine (TCM), with its personalized treatment based on syndrome differentiation, shows potential to modulate multiple pathological pathways implicated in DKD. This review provides a detailed examination of DKD pathogenesis and the progress in TCM research, offering valuable insights for DKD treatment research and clinical practice.
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Li et al. (2025) studied this question.
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