Why the study?
Does time to thrombolytic treatment impact mortality, reinfarction, infarct size, and ejection fraction in patients with acute myocardial infarction?
Does time to thrombolytic treatment impact mortality, reinfarction, infarct size, and ejection fraction in patients with acute myocardial infarction?
Earlier thrombolysis (within 2 hours) is associated with smaller infarct size and better ejection fraction, while mortality benefits are seen across all time intervals up to 12 hours, despite a higher reinfarction rate with earlier treatment.
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Supports expedited thrombolysis in AMI; leaves open causality and relevance amid modern reperfusion strategies.
Panithaya Chareonthaitawee (2000) studied this question.
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