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September 9, 2009Cancer ResearchOpen Access

Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation

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Authors

DKDae Joon KimThe University of Texas Rio Grande ValleyKKKen KataokaOkayama University of ScienceDRDharanija RaoPfizer (United States)

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Kim et al. (2009) studied this question.

synapsesocial.com/papers/6a7f704bc18c347100657101https://doi.org/10.1158/0008-5472.can-09-1180
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidermal Growth Factor Receptor-Mediated Activation of Stat3 during Multistage Skin Carcinogenesis2004 · 166 citations
  2. 2Targeted disruption of Bcl‐x<sub>L</sub> in mouse keratinocytes inhibits both UVB‐ and chemically induced skin carcinogenesis2009 · 36 citations
  3. 3Critical Aspects of Initiation, Promotion, and Progression in Multistage Epidermal Carcinogenesis1993 · 121 citations
  4. 4Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.1991 · 577 citations
  5. 5Signal Transducer and Activator of Transcription 3 Is a Key Regulator of Keratinocyte Survival and Proliferation following UV Irradiation2005 · 102 citations