A simple, clean and environmentally benign route to the synthesis of 3‐cyanopyridines is described via a one‐pot multi‐component reaction of 3,4‐dimethoxyacetophenone, malonitrile or ethylcyanoacetate, aldehyde and ammonium acetate using heteropolyacids as heterogeneous and recyclable catalysts in very good yields.
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Heravı et al. (2009) studied this question.
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