Safety assessment demonstrates toxicological clearance of 2-butyl-4,4,6-trimethyl-1,3-dioxane across human and environmental endpoints, indicating low risk in fragrance use.
• 2-Butyl-4,4,6-trimethyl-1,3-dioxane; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.
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Api et al. (2024) studied this question.
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