February 1, 2004Clinical Orthopaedics and Related Research
Synovial Sarcoma
Population
135 consecutive patients with extremity and truncal synovial sarcomas
Design
Cohort
Follow-up
median 78 months (range, 20–420 months)
Authors
Discussion
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Member takes
Implication
Tumor size >5 cm marks higher mortality risk in synovial sarcoma; leaves open whether it should guide therapy intensity in prospective studies.
Structured PICO
P
Population
135 consecutive patients with extremity and truncal synovial sarcomas (73% newly diagnosed localized primary, 7% locally recurrent, 20% metastatic)
O
Outcome
Overall survivalhard clinical
Primary tumor size is a strong independent prognostic factor for survival in patients with synovial sarcoma, suggesting that tumors larger than 5 cm warrant more aggressive therapy.
Cite This Study
Deshmukh et al. (2004) studied this question.