Why the study?
Are there significant arteriovenous differences in the concentrations of lactate, pyruvate, glucose, and free fatty acids across the pulmonary circulation in patients with acquired heart disease?
Population
Patients with acquired heart disease
Design
Cross-sectional
Authors
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Minor glucose gradient across pulmonary circulation warrants no clinical action in heart disease; leaves open its metabolic relevance pending prospective studies.
Are there significant arteriovenous differences in the concentrations of lactate, pyruvate, glucose, and free fatty acids across the pulmonary circulation in patients with acquired heart disease?
In patients with acquired heart disease, glucose concentration is slightly higher in brachial arterial blood compared to mixed venous blood, suggesting some pulmonary glucose metabolism or release, whereas other measured metabolites show no significant difference.
Harris et al. (1963) studied this question.