Erythrocytes carbamylated in vitro with sodium cyanate have significantly increased electrophoretic mobility. Species differences were noted between human, rabbit, and rat erythrocytes. In contrast to other agents'increasing net negative surface charge, cyanate does not destroy erythrocyte viability. It is postulated that carbamylation of surface amino groups results in an increased net negative charge.
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Durocher et al. (1973) studied this question.