A new, readily available monophosphine tetrafluoroborate salt [ L2 ⋅ HBF 4 ] was developed for the palladium‐catalyzed amination reaction of aryl chlorides in moderate to high yields with the cheap and easily available potassium hydroxide as the base. The reaction enjoys a wide scope, lower reaction temperatures, shorter reaction times, high yields, and low catalyst loading when compared to some of same amination reactions reported in the literature. Based on a kinetic study, 31 P NMR measurements, and DFT calculations, a mechanism involving a 1:1 Pd/L species is proposed.
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Lü et al. (2011) studied this question.
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