Left ventricular longitudinal function and hyperkinetic profile: a new echo world to explore?

Q: What is the clinical evidence from this study?

Study design: Letter. Population: Critical illness. Intervention: Echocardiographic assessment of hyperdynamic left ventricular profile vs. Normal left ventricular systolic function.

Filipe Gonzalez; SIDDHARTH DUGAR; Michel Slama; Filippo Sanfilippo

doi:10.1186/s13054-026-06244-x

August 13, 2026Critical CareOpen Access

Left ventricular longitudinal function and hyperkinetic profile: a new echo world to explore?

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Key result

The authors propose that evaluating hyperdynamic left ventricular function using longitudinal markers could provide valuable prognostic information in critically ill patients.

Key Points

To evaluate the clinical relevance of left ventricular longitudinal function markers and highlight the prognostic implications of hyperdynamic phenotypes in critically ill patients.
Commentary evaluating an intensive care unit (ICU) cohort study of 377 patients assessed within 24 hours of ICU admission.
Assessed four left ventricular systolic parameters: ejection fraction (LVEF), global longitudinal strain (GLS), mitral annular plane systolic excursion (MAPSE), and tissue Doppler imaging systolic velocity (TDI-S’).
In the referenced cohort, 77% of patients (n = 290) presented with preserved LVEF (≥ 50%), while previous evidence indicates a U-shaped mortality curve with higher mortality in severe dysfunction (LVEF < 25%) and hyperdynamic states (LVEF ≥ 70%).
A cited meta-analysis identified an 18.2% pooled prevalence of hyperdynamic left ventricular state (LVEF ≥ 70%) in septic patients, associated with increased short-term mortality (odds ratio 2.37) compared to normal systolic function.

Structured PICO

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Population

Critically ill ICU patients

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Implication

This commentary highlights the need to explore the prognostic significance of hyperdynamic left ventricular function and its correlation with longitudinal echocardiographic markers in critically ill patients.

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Cite This Study

Gonzalez et al. (2026) conducted a letter in Critical illness. Echocardiographic assessment of hyperdynamic left ventricular profile vs. Normal left ventricular systolic function was evaluated. The authors propose that evaluating hyperdynamic left ventricular function using longitudinal markers could provide valuable prognostic information in critically ill patients.

synapsesocial.com/papers/6a8038a675c2e31742c86f85 https://doi.org/10.1186/s13054-026-06244-x

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Left ventricular longitudinal function and hyperkinetic profile: a new echo world to explore?

Key Points

Structured PICO

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Implication

Abstract

Discussion

Cite This Study

Left ventricular longitudinal function and hyperkinetic profile: a new echo world to explore?

Key Points

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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