Primary cardiac myxofibrosarcoma is an exceptionally rare malignancy that can present solely with brain metastases and no cardiopulmonary symptoms, carrying a high risk of hemorrhagic progression and poor prognosis.
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Cardiac imaging may warrant consideration in unexplained hemorrhagic brain metastases; leaves open optimal diagnostic and therapeutic strategies.
Herein we describe the case of a young patient who presented with a recent history of epilepsy due to multiple brain lesions; he did not complain about any cardiopulmonary impairments. The patient died as a consequence of hemorrhagic progression of brain metastatic disease. Regardless of a thorough investigation, the heart tumor remained occult. Primary cardiac tumors are very rare entities. Most of these are benign, but approximately 25% are malignant, and the majority of these are sarcomas. Myxofibrosarcoma and osteosarcoma are exceptionally rare. To date, we find only small series of cardiac myxofibrosarcoma, and to our knowledge, this one exceptionally presented with multiple brain metastatic lesions without cardiopulmonary symptoms.
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Badaloni et al. (2017) studied this question.
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