Oxidative stress and too many superoxide radical anions O2.− can cause considerable damage to organisms. Superoxide dismutase (SOD) enzymes with Mn- or Cu/Zn centers can repress the accumulation of radicals. SOD mimics such as 1 are described that could possibly find use in the treatment of cardiovascular diseases and inflammation.
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Roland Krämer (2000) studied this question.
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