Efficiency of Atorvastatin in the Protection of Anthracycline-Induced Cardiomyopathy

“There are some animal studies that show, you know, that statins can decrease the toxicity of anthracyclines. There are some retrospective studies that show that patients who were on statins had less heart failure than patients who were not. And then at the time that we started, there was this small prospective trial that enrolled 40 patients, and that was very encouraging.”

“We wanted to test statins because there was some experimental evidence from animal studies and in retrospective studies and a small prospective study that implied there would be some cardio-protective properties of atorvastatin.”