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As many as 1 billion cases of rhinosinusitis occur in the United States each year, costing more than $5 billion dollars in medical expenditures. This common disease affects approximately 16% of the population annually, resulting in missed work and lost productivity. This chapter reviews the increasing prevalence of this disabling disease, the huge economic impact it has on our society, and the cost effectiveness of several management strategies used by physicians.
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Gross et al. (2001) studied this question.
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