H1N1 influenza-related myositis in adults can present atypically with four-extremity involvement, including distal upper extremities, but follows a benign course that resolves rapidly with supportive care.
Alerts clinicians to atypical adult H1N1 myositis; leaves open broader characterization beyond this small case series.
Acute viral myositis is a rare condition that occurs during the recovery phase of an illness, most commonly influenza. It is characterized by muscle pain and weakness with an isolated laboratory finding of elevated serum creatine kinase (CK). We describe three previously healthy patients who were hospitalized after developing myositis following influenza-like illness during the 2009 influenza A (H1N1) virus pandemic. All experienced myalgias and weakness in all four extremities, including distal upper extremities, associated with an elevated CK level that resolved along with their myalgias and weakness within one week with supportive care. These cases serve as a reminder that influenza-related myositis may have atypical characteristics depending on the strain of influenza, and clinicians should be open to this possibility when new outbreaks occur.
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Gibson et al. (2013) studied this question.
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